Point Nemo, in the South Pacific, is the spot in the ocean farthest from any land, about 2,700 km from the nearest coast. The International Space Station, orbiting roughly 400 km up, sometimes passes far closer than any human on the ground. Remote and rarely visited, the area also serves as a graveyard for retired spacecraft.
On 27 August 1883, the eruption of the Indonesian volcano Krakatoa was heard as far away as Rodrigues Island, nearly 4,800 km away. Its pressure wave was picked up by barometers worldwide and circled the globe several times. The tsunamis that followed killed more than 36,000 people.
The deepest known point in the ocean, Challenger Deep, lies roughly 10,900 m below the Pacific surface. Drop Everest in and its summit would still sit about 2 km underwater. Down there, the pressure is more than 1,000 times what you feel at sea level, roughly a tonne pressing on every square centimetre.