It's false, and brain imaging shows it: over a day, virtually every region of the brain becomes active, even during sleep. Damage to a tiny area, wherever it is, almost always has consequences. And evolution would never have kept such an energy-hungry organ if 90% of it were useless.
Every day, your kidneys filter around 180 liters of blood plasma, about a bathtub's worth. Yet you only have about 3 liters of plasma, so it passes through your kidneys some sixty times a day. Over 99% of the filtered water is reabsorbed, leaving just one to two liters of urine.
A 70 kg adult is made of about 7 × 10²⁷ atoms, or seven billion billion billion. The observable universe is thought to hold on the order of 10²² to 10²⁴ stars. Even with the high estimate, you contain thousands of times more atoms than there are stars in the entire visible cosmos.